Protective Effect of Vitamin E and Selenium on the Liver, Heart and Aorta

This study was carried on four groups of Wistar male rats (20 of each), to evaluate the protective effect of vitamin E and selenium on the structure and biochemical alterations of the liver, heart and aorta. Group I is control, Group II fed high fat and vitamin E and selenium deficient diet as control positive group. Group III (protective) given 100 mg and 0.1 mg/kg b.w/day for 6months, vitamin E and selenium respectively with high fat diet. Group IV were injected intra peritoneal Vitamin E and selenium 1 g/100 g b.w for 6 months after feeding high fat diet for 6 months. At the end of experimental design, histological section from liver, heart and aorta and so serum changes in metabolites of heart and liver were examined. The tissues of the control positive group showed accumulation of small and large fat globules in the hepatocytes, loss of striation in the cardiac muscles and thickening in the wall of the aorta with loss of the elasticity of the elastic membranes in the tunica media. While the addition of vitamin E and selenium (vitamin E 100mg. kg/bw and selenium 0.1mg. kg/b.w) to the ration of the third group (protective group), prevent the severe hazard effect that occurred in the second (control positive group).The injections of vitamin E and selenium 1ug/100g for 6 months lead to decrease the degenerative changes in the heart, liver and aorta with regeneration of these cells. Vitamin E and selenium administered or injected to Wistar rats decreased significantly the increase in serum levels of LDL, CPK, GOT induced by feeding high fat diet alone. These results collectively Animal species in this issue Common quail (Coturnix coturnix) Kingdom: Animalia & Phylum: Chordata & Class: Aves & Order: Galliformes & Family: Phasianidae & Genus: Coturnix & Species: Coturnix coturnix & Coturnix japonica Quail is a collective name for several genera of mid-sized birds generally considered in the order Galliformes. Old World quail are found in the family Phasianidae, and New World quail are found in the family Odontophoridae. The buttonquail are not quail at all, are named more for their superficial resemblance to quail, and are members of the Turnicidae family, more closely related to the Charadriiformes. The King Quail, a member of the Old World quail, is often sold in the pet trade and is commonly referred to there as a "button quail". Many of the common larger species are farm raised for table food or egg consumption, and are hunted on game farms or in the wild, where they are sometimes artificially stocked to supplement the wild population, or extend into areas they are normally not found naturally. The collective noun for a group of quail is a covey or bevy. Source: Wikipedia